- State Route 905The main east-west road across Otay Mesa, leading to the border and to Interstates 805 and 5.
- Interstate 805 and Interstate 5Connect to San Diego and the South Bay.
- State Route 125A toll road to the north and east.
- The TrolleyThe San Diego Trolley Blue Line runs from San Ysidro to downtown.
- AirportsSan Diego International Airport and, through Cross Border Xpress, Tijuana International Airport.
Tip
Test your commute at your usual hours before you buy.
More in Otay Mesa Guide
- Otay Mesa Parks and Open Space — Trails, reservoirs, nature parks and the coast, all within a short drive.
- The Border, the Airport and What They Mean Locally — The Otay Mesa port of entry, the Cross Border Xpress and Brown Field, three landmarks that shape the area.
- Shopping and Dining Near Otay Mesa — Outlets, town centers, big-box stores and some of the best casual dining in the South Bay.
- Otay Mesa Community Events — Community gatherings, farmers markets and regional events near Otay Mesa.
General information only. Hours, menus, schedules and events change, so confirm details before you go. Places are named for information only and are not endorsements or advertisements.